NASDAQ Biotechnology Index ($NBI)

End of Day Index Report for 3/18/10

Data Period (Except as noted, statistics reflect the most current day's trading) Daily Weekly Monthly Quarterly
Open 936.91 936.71 887.21 851.83
High 942.46 942.46 942.46 942.46
Low 936.51 929.99 887.13 826.84
Close 940.70 940.70 940.70 940.70
Net change since last period end through current day 4.00 3.86 61.84 97.13
Net change of previous completed period -2.04 17.36 18.72 3.96
         
Total Volume of Component Issues 1,345,404 6,960,259 25,155,799 83,798,371
         
1 Year Price High 942.46 942.46 942.46 942.46  
1 Year Price High Date 3/18/10 3/18/10 3/18/10 3/18/10
1 Year Price Low 643.60 643.60 605.38 605.38
1 Year Price Low Date 4/23/09 4/24/09 3/31/09 3/31/09
         
Trend Pivot 910.61 867.54 787.93 796.23
Current Trend Up Up Up Up
      Trend Gain/Loss as of Period End 65.80 132.61 132.79 101.09
      Trend Life (Periods) 16 18 4 2
      Trend Begin Date 2/24/10 11/13/09 11/30/09 9/30/09
         
         
         
Composite Statistics  
       
      % Of Component Issues In Uptrends 72.80% 77.60% 70.40% 53.60%
      Total Up Trends 91 97 88 67
            New Up Trends 5 2 17 11
      Total Down Trends 34 28 37 58
            New Down Trends 8 6 2 3
         
      Component Issues Traded 125 125 125 125
      % Of Component Issues Advancing 43.20% 51.20% 80.80% 64.80%
      Advancing Issues 54 64 101 81
      Declining Issues 66 59 24 44
      Unchanged Issues 5 2 0 0
      % Advancing Volume 51.11% 47.14% 74.70% 69.60%
      Advancing Volume 687,664 3,280,811 18,792,369 58,322,407
      Declining Volume 635,495 3,416,954 6,363,430 25,475,964
      Unchanged Volume 0 0 0 0
         
      New Component 1 Year Highs 10 23 34 36
      New Component 1 Year Lows 1 2 3 10
         
      Component Issues Above/Below Period Moving Average        
     

     

% Above 200 Period Moving Average 66.40% 51.20% 64.00% 89.60%
                  Issues Above 83 64 80 112
                  Issues Below 42 61 45 13
     

     

% Above 50 Period Moving Average 69.60% 70.40% 52.00% 58.40%
                  Issues Above 87 88 65 73
                  Issues Below 38 37 60 52
     

     

% Above 30 Period Moving Average 75.20% 68.80% 56.00% 56.00%
                  Issues Above 94 86 70 70
                  Issues Below 31 39 55 55
     

     

% Above 18 Period Moving Average 72.80% 74.40% 69.60% 51.20%
                  Issues Above 91 93 87 64
                  Issues Below 34 32 38 61
     

     

% Above 9 Period Moving Average 56.00% 74.40% 68.00% 58.40%
                  Issues Above 70 93 85 73
                  Issues Below 53 32 40 52
     

     

% Above 4 Period Moving Average 47.20% 69.60% 73.60% 63.20%
                  Issues Above 59 87 92 79
                  Issues Below 66 38 33 46
         
 

Components

Trend As Of Period End

Data Period (Except as noted, statistics reflect the most current day's trading) Daily Weekly Monthly Quarterly
Nasdaq Biotechnology Index® ($NBI)   2/24/10 11/13/09 11/30/09 9/30/09
Acorda Therapeutics Inc. (ACOR) 3/1/10 11/6/09 12/31/09 /0/
Adolor Corporation (ADLR) 3/18/10   2/26/10 3/18/10   9/29/06
Affymetrix Inc (AFFX) 3/12/10 2/5/10 2/26/10 3/31/06
Akorn Inc (AKRX) 3/15/10 3/12/10 2/29/08 12/31/08
Albany Molecular Research Inc. (AMRI) 3/8/10 3/12/10 10/31/08 12/31/08
Alexion Pharmaceuticals Inc. (ALXN) 2/16/10 2/12/10 5/29/09 3/31/06
Alexza Pharmaceuticals Inc. (ALXA) 3/12/10 12/31/09 2/26/10 9/30/09
Alkermes Inc. (ALKS) 2/26/10 12/4/09 1/29/10 12/31/07
Allos Therapeutics Inc. (ALTH) 3/10/10 1/8/10 1/29/10 12/29/06
Alnylam Pharmaceuticals Inc. (ALNY) 3/17/10 2/12/10 8/31/09 12/31/09
Advanced Magnetics Inc (AMAG) 3/18/10   2/5/10 1/29/10 3/18/10  
Amgen Inc (AMGN) 3/16/10 1/29/10 3/18/10   3/31/09
Amylin Pharmaceuticals Inc. (AMLN) 2/26/10 11/27/09 12/31/09 3/31/08
Arena Pharmaceuticals Inc. (ARNA) 3/17/10 2/26/10 9/30/09 12/31/07
ARIAD Pharmaceuticals Inc. (ARIA) 2/9/10 2/12/10 11/30/09 3/30/07
ArQule Inc. (ARQL) 2/23/10 3/5/10 9/30/09 9/30/09
Array BioPharma Inc. (ARRY) 3/11/10 12/18/09 12/31/07 12/31/07
Auxilium Pharmaceuticals Inc. (AUXL) 3/17/10 3/12/10 2/26/10 /0/
BioCryst Pharmaceuticals Inc. (BCRX) 3/8/10 3/18/10   4/30/09 3/30/07
Biodel Inc (BIOD) 3/18/10   3/5/10 9/30/08 /0/
Biogen Idec Inc (BIIB) 2/26/10 12/4/09 12/31/09 9/30/09
BioMarin Pharmaceutical Inc. (BMRN) 3/1/10 11/20/09 1/29/10 3/18/10  
Biomimetic Therapeutics Inc. (BMTI) 3/11/10 3/5/10 7/31/09 /0/
Beijing Med-Pharm Corp (BJGP) 3/15/10 11/20/09 12/31/09 12/31/09
Cadence Pharmaceuticals Inc (CADX) 3/18/10   3/18/10   3/18/10   /0/
Cardiome Pharma Corporation (CRME) 2/26/10 12/18/09 1/29/10 9/30/08
Applera Corp-Celera Genomics (CRA.O) 3/10/10 3/5/10 10/31/08 12/31/08
Celgene Corporation (CELG)   2/11/10 2/12/10 1/29/10 9/30/02
Cephalon Inc (CEPH) 2/9/10 12/11/09 2/26/10 3/18/10  
China Sky One Medical Inc. (CSKI) 3/17/10 3/18/10   11/30/09 /0/
Columbia Laboratories Inc. (CBRX) 3/16/10 1/15/10 9/30/08 9/30/08
Crucell NV (CRXL) 3/1/10 3/5/10 1/30/09 3/18/10  
Cubist Pharmaceuticals Inc. (CBST)   2/25/10 1/15/10 2/26/10 3/18/10  
Cypress Bioscience Inc. (CYPB) 3/18/10   8/21/09 10/30/09 12/31/09
Cytokinetics Incorporated (CYTK) 3/18/10   3/5/10 3/18/10   12/31/09
Dendreon Corporation (DNDN) 2/11/10 1/8/10 4/30/09 6/30/09
DepoMed Inc. (DEPO) 2/25/10 3/5/10 3/18/10   9/29/06
Discovery Laboratories Inc. (DSCO) 2/18/10 12/11/09 10/30/09 6/30/06
Durect Corporation (DRRX) 2/11/10 2/19/10 10/31/08 12/31/08
Dyax Corp. (DYAX) 2/26/10 3/5/10 11/30/09 3/18/10  
Endo Pharmaceuticals Holdings Inc. (ENDP) 2/12/10 2/26/10 2/26/10 3/31/08
Enzon Pharmaceuticals Inc. (ENZN) 3/1/10 3/12/10 9/30/09 6/30/09
Exelixis Inc. (EXEL) 3/9/10 3/12/10 8/31/09 12/31/07
Facet Biotech Corp. (FACT) 3/10/10 3/5/10 /0/ /0/
Flamel Technologies S.A. (FLML) 3/11/10 3/12/10 1/29/10 6/29/07
Genomic Health Inc. (GHDX) 2/9/10 3/5/10 1/29/10 /0/
Gen-Probe Incorporated (GPRO) 2/16/10 2/19/10 1/29/10 12/31/08
Genzyme General (GENZ) 2/11/10 1/8/10 11/28/08 12/31/08
Geron Corporation (GERN) 3/1/10 3/5/10 3/18/10   3/18/10  
Gilead Sciences Inc. (GILD) 3/17/10 1/15/10 1/29/10 12/31/98
GTx Inc. (GTXI) 3/2/10 3/5/10 1/30/09 12/31/09
Halozyme Therapeutics Inc (HALO) 3/1/10 3/5/10 3/18/10   /0/
Hi-Tech Pharmacal Co. Inc. (HITK) 3/18/10   3/5/10 6/30/09 9/30/09
Human Genome Sciences Inc. (HGSI) 2/11/10 3/5/10 7/31/09 9/30/09
Idenix Pharmaceuticals Inc. (IDIX) 3/16/10 1/8/10 2/27/09 3/31/08
Illumina Inc. (ILMN) 3/1/10 1/15/10 1/29/10 12/31/04
ImmunoGen Inc. (IMGN) 3/1/10 3/18/10   3/31/09 3/31/09
Immunomedics Inc. (IMMU) 3/18/10   2/26/10 1/29/10 6/30/09
Impax Laboratori (IPXL) 2/10/10 /0/ /0/ /0/
Incyte Corporation (INCY) 2/26/10 5/29/09 8/31/09 9/30/09
Inspire Pharmaceuticals Inc. (ISPH) 3/16/10 2/12/10 11/30/09 6/30/09
InterMune Inc. (ITMN)   3/5/10 3/5/10 1/29/10 3/18/10  
Isis Pharmaceuticals Inc. (ISIS) 3/9/10 9/4/09 9/30/09 12/31/09
Lexicon Genetics Incorporated (LXRX) 2/24/10 3/12/10 3/18/10   12/31/03
Life Technologies Corporation (LIFE) 2/12/10 2/19/10 4/30/09 6/30/09
Ligand Pharmaceuticals Incorporated (LGND) 3/12/10 1/8/10 3/30/07 3/30/07
Luminex Corporation (LMNX) 2/9/10 2/12/10 3/18/10   9/30/09
MannKind Corporation (MNKD) 3/15/10 3/18/10   11/30/09 3/31/08
Maxygen Inc (MAXY) 3/1/10 3/5/10 1/29/10 9/30/09
Medivation Inc. (MDVN) 3/3/10 3/5/10 3/18/10   3/18/10  
Micormet Inc (MITI) 3/11/10 1/8/10 4/30/09 9/30/09
Middlebrook Pharmaceutical Inc. (MBRK) 3/12/10 8/7/09 7/31/08 6/29/07
Momenta Pharmaceuticals Inc. (MNTA) 3/8/10 12/4/09 12/31/09 3/18/10  
Mylan Laboratories (MYL.O)   2/11/10 8/14/09 2/27/09 9/30/09
Myriad Genetics Inc. (MYGN) 2/26/10 3/12/10 7/31/09 3/31/06
Nabi Biopharmaceuticals (NABI) 2/10/10 8/7/09 11/30/09 12/31/09
Nektar Therapeutics (NKTR) 2/11/10 11/6/09 5/29/09 3/18/10  
Neurocrine Biosciences Inc. (NBIX) 3/17/10 3/12/10 12/31/07 6/30/06
Novavax Inc. (NVAX) 3/18/10   9/25/09 11/30/09 12/31/09
NPS Pharmaceuticals Inc. (NPSP) 3/1/10 2/19/10 2/27/09 3/31/04
Obagi Medical Products Inc. (OMPI)   3/1/10 3/5/10 7/31/09 /0/
ONYX Pharmaceuticals Inc. (ONXX) 3/1/10 3/5/10 3/18/10   12/31/09
Optimer Pharmaceuticals Inc. (OPTR) 2/26/10 3/5/10 11/28/08 /0/
Orexigen Therapeutics Inc (OREX) 3/17/10 3/12/10 1/29/10 /0/
OSI Pharmaceuticals Inc. (OSIP)   2/12/10 1/15/10 2/26/10 3/18/10  
Osiris Therapeutics (OSIR) 2/26/10 3/18/10   3/31/09 3/18/10  
Pain Therapeutics (PTIE)   3/17/10 2/5/10 3/18/10   12/31/08
Protein Design Labs Inc. (PDLI) 3/11/10 3/12/10 11/30/09 9/28/07
Perrigo Company (PRGO) 3/17/10 8/21/09 9/30/09 6/30/09
Pharmasset Inc. (VRUS)   3/9/10 1/29/10 7/31/09 /0/
Poniard Pharmaceuticals Inc (PARD) 3/18/10   11/20/09 11/30/09 12/31/09
Pozen Inc. (POZN) 3/16/10 3/5/10 3/18/10   9/28/07
Progenics Pharmaceuticals Inc. (PGNX) 3/5/10 1/15/10 11/30/07 12/31/07
Qiagen N.V. (QGEN) 2/25/10 3/5/10 7/31/09 6/30/09
QLT Inc. (QLTI) 2/11/10 11/27/09 7/31/09 12/31/09
Questcor Pharmaceuticals Inc. (QCOR)   2/24/10 2/26/10 3/18/10   12/31/07
Regeneron Pharmaceuticals Inc. (REGN) 2/18/10 12/18/09 12/31/09 6/30/09
Rigel Pharmaceuticals Inc. (RIGL) 3/12/10 2/19/10 3/18/10   12/31/08
Salix Pharmaceuticals Ltd. (SLXP) 2/24/10 6/5/09 3/31/09 9/30/09
Sangamo Biosciences Inc (SGMO) 3/1/10 3/5/10 3/18/10   12/31/09
Santarus Inc. (SNTS) 2/23/10 3/5/10 5/29/09 12/31/09
Savient Pharmaceuticals Inc (SVNT) 2/24/10 3/5/10 12/31/09 6/30/09
Seattle Genetics Inc. (SGEN) 2/24/10 2/12/10 3/18/10   9/29/06
Sequenom Inc (SQNM) 3/16/10 1/8/10 2/27/09 6/30/09
Shire Pharmaceuticals Group plc (SHPGY) 2/11/10 5/22/09 8/31/09 9/30/09
SIGA Technologies Inc. (SIGA) 2/11/10 3/12/10 1/30/09 6/30/08
Spectrum Pharmaceuticals Inc (SPPI) 3/1/10 3/5/10 2/26/10 6/30/09
StemCells Inc. (STEM) 3/16/10 3/12/10 10/30/09 6/30/06
SuperGen Inc. (SUPG) 3/1/10 1/29/10 7/31/09 3/30/07
Synta Pharmaceuticals Corp. (SNTA) 3/2/10 3/5/10 3/18/10   /0/
Targacept Inc. (TRGT) 3/2/10 1/8/10 7/31/09 /0/
Techne Corporation (TECH) 2/24/10 3/5/10 3/18/10   12/31/09
Teva Pharmaceutical Industries Limited (TEVA)   3/18/10   11/6/09 5/29/09 3/31/99
Medicines Company (The) (MDCO) 2/26/10 3/5/10 10/31/08 12/31/08
Theravance Inc (THRX) 2/24/10 3/5/10 1/29/10 6/30/08
United Therapeutics Corporation (UTHR) 3/15/10 11/20/09 12/31/09 6/30/09
Vanda Pharmaceuticals Inc. (VNDA) 3/10/10 3/5/10 5/29/09 /0/
Vertex Pharmaceuticals Incorporated (VRTX) 3/18/10   2/19/10 1/30/09 3/31/08
Vical Inc (VICL) 2/11/10 2/12/10 12/31/09 12/31/09
ViroPharma Incorporated (VPHM) 2/12/10 12/18/09 2/26/10 3/18/10  
Vivus Inc. (VVUS) 3/1/10 3/5/10 5/29/09 6/30/09
Warner Chilcott Limited. (WCRX) 3/11/10 3/18/10   7/31/09 /0/
XenoPort Inc. (XNPT) 3/12/10 2/19/10 10/31/08 12/31/08
XOMA Ltd. (XOMA) 2/25/10 9/4/09 1/31/08 12/31/03
ZymoGenetics Inc. (ZGEN) 3/18/10   3/18/10   11/30/09 3/30/07
 
    
   
 
   
   
   

 


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